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kilomentor | 27 September, 2008 10:28
Innovator pharmaceutical companies today are experiencing difficulties like never before.
A medical need is only unmet when there is no treatment for the condition. An improved therapy competes with the previous treatment and to-day that treatment is increasingly becoming generic. The choice is no longer between the one treatment at any cost or nothing. It is now between the relative costs of different treatments. With second and higher generation drugs, there is no treatment monopoly. The old breakthrough medicine, now genericized, remains as a viable option. When there is only one realistic treatment, we are all blackmailed to prove our love for the patient is authentic. When there are treatment options, we re-enter the rational world.
Never have so many scientists been looking for new medicines. Never have they been raised so high upon the shoulders of prior generations of scientists. Never have we worked with tools of such power. Never have we had so much data so instantly at hand. But still we cannot increase the output of drug products.
Perhaps our human biology has limits to how it can be tweaked by any pure drug substance? Perhaps the biological differences among us as individual human specimens are so great that what is a useful treatment for many will always be lethal for a few.
Whether we are innovators or genericizers we are all ultimately in the same boat. If innovators fail, then not so far down the road there can be no new generic products.
As process development specialists in the pharmaceutical industry we can only fill our brains with the best information we can find, be unselfish in teaching our colleagues, and thank God we have such spiritually stimulating work in an awesome universe.
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