kilomentor | 12 April, 2012 13:50
The Kilomentor educational blog is likely to have even more visitors starting next week. A letter from the author appearing in the letters section of the Journal of Chemical & Engineering News wil comment on the utility of blogs for educational purposes. Therefore, a review of the history, purpose, and perspective of the blog may be appropriate.
The Kilomentor blog was begun in 2006. The goal was to provide training and updating in the methods for chemical process development, emphasizing scale up of organic synthesis, particularly for high value pharmaceutical products. The author recognized that there were textbooks, symposia, and courses for this purpose but they were expensive and not equally available anywhere in the world. Moreover, in academia, the treatment of chemical process development was neither widespread nor generally thorough enough. The Kilomentor blog would be free, have post graduate content, and be available wherever access to the world wide web was possible.
The particular perspective of this blog was that designing synthetic routes selection has become easier than in in the past. Today, ever since electronic sub-structure searching became readily available, finding promising potential schemes has been simplified. What has not been made easier is choosing between these hypothetical process routes and finding rugged/fast methods of isolating process intermediates. Kilomentor has chosen to highlight techniques that both work on scale and make isolating clean intermediates easier. The articles encourage development chemists and chemical engineers to choose processes for scaling that comprise more of such easily purified intermediates. It has suggested that routes containing more of these rugged intermediates may even be preferable to processes with fewer apparent steps. Thus routes that can have higher throughput tend to win out over routes that just have fewer ‘ on paper’ transformations.
The Kilomentor blog has been well received. It has had more than 184,000 visits since its start and there are now more than 115 separate blog articles. Visits, in 2012, have reached about 200 per day. A search tool on the site will look for key words and identify relevant articles.
Thanks for participating; and if you are new, then welcome!