kilomentor

Nitriles Separated by Competitive Reaction and then Simple Extraction

kilomentor | 15 December, 2009 18:55

The Kilomentor Blog is now being continued and updated at www.kilomentor.com This particular article ca be found at http://www.kilomentor.com/2009/12/nitriles-separated-by-competitive-reaction-and-then-simple-extraction

 

Comments

Re: Nitriles Separated by Competitive Reaction and then Simple Extraction

peter | 16/12/2009, 07:52

To me it sounds like very very specific issue which is hardly encountered on regular basis. However, the concept of separating isomers based on different reactivity (stemming from either steric of electronic effects) is certainly useful.

Kilomentor to peter

kilomentor | 19/12/2009, 06:04

Peter is correct. The purpose is to get us thinking about using reactivity for rugged, simple separations. The selectively formed product should be separable from the unreacted substrate by some rapidinexpensive step like organic/water extraction as in the example where the product tetrazole is soluble in aqueous base.

Add comment

authimage

 
Powered by LT - Design by BalearWeb